Enzymatic and immunochemical characterization of Bothrops insularis venom and its neutralization by polyspecific Bothrops antivenom.

@article{Lira2007EnzymaticAI,
  title={Enzymatic and immunochemical characterization of Bothrops insularis venom and its neutralization by polyspecific Bothrops antivenom.},
  author={Marcela S Lira and Maria de Fatima Domingos Furtado and Luciana Martins and Monica Lopes-Ferreira and Marcelo Larami Santoro and K{\'a}tia Cristina Barbaro},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2007},
  volume={49 7},
  pages={982-94}
}
Herein we compared the biological activities of Bothrops insularis and Bothrops jararaca venoms as well as their neutralization by polyspecific Bothrops antivenom (PBA). On account of that, we investigated their antigenic cross-reactivity and the neutralization of lethal, myotoxic and defibrinating activities by polyspecific and species-specific antivenoms. Silver-stained SDS-PAGE gels evidenced many common bands particularly above 47 kDa between B. jararaca and B. insularis venoms. However… CONTINUE READING

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