Enzymatic activity and brine shrimp lethality of venom from the large brown spitting cobra (Naja ashei) and its neutralization by antivenom

@article{Okumu2020EnzymaticAA,
  title={Enzymatic activity and brine shrimp lethality of venom from the large brown spitting cobra (Naja ashei) and its neutralization by antivenom},
  author={Mitchel Otieno Okumu and James Mucunu Mbaria and Joseph Kangangi Gikunju and Paul Gichohi Mbuthia and Vincent Odongo Madadi and Francis Okumu Ochola},
  journal={BMC Research Notes},
  year={2020},
  volume={13}
}
Naja ashei is a snake of medical importance in Kenya, Ethiopia, Somalia, Uganda, and Tanzania. Little is known about the enzymatic (snake venom phospholipases A2; svPLA2’s) and toxic (lethal) activities of N. ashei venom and crucially, the safety and capacity of available antivenom to neutralize these effects. This study aimed to determine the enzymatic and toxic activities of N. ashei venom and the capacity of Indian and Mexican manufactured antivenoms to neutralize these effects. The protein… Expand
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