Enzymatic Decoration of Prebiotic Galacto-oligosaccharides (Vivinal GOS) with Sialic Acid Using Trypanosoma cruzi trans-Sialidase and Two Bovine Sialoglycoconjugates as Donor Substrates.

Abstract

Decoration of prebiotic galacto-oligosaccharides (GOS) with sialic acid yields mixtures of GOS and sialylated GOS (Sia-GOS), novel products that are expected to have both prebiotic and antiadhesive functionalities. The recombinantly produced trans-sialidase enzyme from Trypanosoma cruzi (TcTS), an enzyme with the ability to transfer (α2-3)-linked sialic… (More)
DOI: 10.1021/acs.jafc.5b01505

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Cite this paper

@article{Wilbrink2015EnzymaticDO, title={Enzymatic Decoration of Prebiotic Galacto-oligosaccharides (Vivinal GOS) with Sialic Acid Using Trypanosoma cruzi trans-Sialidase and Two Bovine Sialoglycoconjugates as Donor Substrates.}, author={Maarten Hotse Wilbrink and Geert A ten Kate and Peter Sanders and Gerrit J. Gerwig and Sander Sebastiaan van Leeuwen and Erik Sallomons and Bert Klarenbeek and Johannes A Hage and Carine A van Vuure and Lubbert Dijkhuizen and Johannis P. Kamerling}, journal={Journal of agricultural and food chemistry}, year={2015}, volume={63 25}, pages={5976-84} }