Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro

@article{Filosto2008EnvironmentallyRC,
  title={Environmentally relevant cadmium concentrations affect development and induce apoptosis of Paracentrotus lividus larvae cultured in vitro},
  author={Simone Filosto and Maria Carmela Roccheri and Rosa Bonaventura and Valeria Matranga},
  journal={Cell Biology and Toxicology},
  year={2008},
  volume={24},
  pages={603-610}
}
Sea urchin embryos and larvae represent suitable model systems on where to investigate the effects of heavy metals on development and cell viability. Here, we tested the toxic effects of low (10−12 M), medium (10−9 M), and high (10−6 M) cadmium chloride concentrations, mimicking unpolluted, moderately and highly polluted seawaters, respectively, on Paracentrotus lividus sea urchins offspring. Larvae were continuously treated from fertilization and inspected at time intervals comprised between… CONTINUE READING