Environmentally induced epigenetic transgenerational inheritance of altered SRY genomic binding during gonadal sex determination

Abstract

A critical transcription factor required for mammalian male sex determination is SRY (sex determining region on the Y chromosome). The expression of SRY in precursor Sertoli cells is one of the initial events in testis development. The current study was designed to determine the impact of environmentally induced epigenetic transgenerational inheritance on… (More)

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Citations per Year

Citation Velocity: 9

Averaging 9 citations per year over the last 2 years.

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