Environmentally Responsive Ophthalmic Gel Formulation of Carteolol Hydrochloride

@article{ElKamel2006EnvironmentallyRO,
  title={Environmentally Responsive Ophthalmic Gel Formulation of Carteolol Hydrochloride},
  author={Amal Hassan El-Kamel and Heba Al-Dosari and Fahad Ibrahim Al-Jenoobi},
  journal={Drug Delivery},
  year={2006},
  volume={13},
  pages={55 - 59}
}
Environmentally responsive gel formulation for ocular controlled delivery of carteolol hydrochloride (HCl) was developed in an attempt to improve ocular bioavailability and hence decrease its systemic absorption and side effects. The viscosity and the ability of the prepared formulations to deliver carteolol HCl in vitro and in vivo were monitored and compared with an aqueous commercial solution. The effect of polymer concentration and drug concentration on the in vitro release of carteolol HCl… 

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