Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress.

@inproceedings{Arif2010EnvironmentalTA,
  title={Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress.},
  author={Ibrahim Abdulwahid Arif and Haseeb Ahmad Khan},
  year={2010}
}
Despite recent advancements in the biomedical fields, the etiology and pathogenesis of Parkinson’s disease (PD) is still poorly understood, though the crucial roles of oxidative stress and impaired mitochondrial respiration have been suggested in the development of PD. The oxidative modification of the proteins of mitochondrial electron transport chain alters their normal function leading to the state of energy crisis in neurons. Exposure of environmental chemicals such as 1-methyl-4-phenyl-1,2… CONTINUE READING

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