Environmental tobacco smoke exposure and risk of allergic sensitisation in children: a systematic review and meta-analysis

  title={Environmental tobacco smoke exposure and risk of allergic sensitisation in children: a systematic review and meta-analysis},
  author={Wojciech Feleszko and Marek Ruszczyński and Joanna Jaworska and Agnieszka Strzelak and Bartłomiej Mateusz Zalewski and Marek Kulus},
  journal={Archives of Disease in Childhood},
  pages={985 - 992}
Background Environmental tobacco smoke (ETS) exposure in children is linked with the development of allergic asthma. However, its influence on allergic sensitisation in children has not been conclusively determined. Objective To systematically review existing evidence of ETS exposure's impact on markers of allergic sensitisation in children. Methods CENTRAL, MEDLINE and EMBASE databases were searched. Included studies assessed following markers of atopic sensitisation: total immunoglobulin E… 

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Exposure in early infancy to ETS increases the risk of IgE sensitisation to indoor inhalant and food allergens, and this effect seemed to be confined to infants of parents without allergic diseases and to Ets exposure during early infancy.

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