Environmental tobacco smoke exposure and brain development: The case of attention deficit/hyperactivity disorder

  title={Environmental tobacco smoke exposure and brain development: The case of attention deficit/hyperactivity disorder},
  author={Linda S Pagani},
  journal={Neuroscience \& Biobehavioral Reviews},
  • L. Pagani
  • Published 1 July 2014
  • Medicine, Psychology
  • Neuroscience & Biobehavioral Reviews

Tables from this paper

Tobacco Use and Smoke Exposure in Children: New Trends, Harm, and Strategies to Improve Health Outcomes

There is no “safe or risk-free” level of tobacco use or exposure in childhood and adolescence, and tobacco use and exposure must be decreased using evidenced-based strategies to improve child health.

The effects of nicotine on human fetal development.

Electronic cigarette use during pregnancy is largely perceived as being safer to use in pregnancy than traditional cigarettes, although there is not adequate evidence to support this claim.

Maternal Smoking during Pregnancy: A Review of the Effects of Maternal Tobacco Use on Fetal Brain Development

Heterogeneity in the timing of brain development, assessment measures used for mother smoking habit and inconsistencies in adjustment for confounders, limits the synthesis and interpretation of findings.

Early Childhood Household Smoke Exposure Predicts Less Task-Oriented Classroom Behavior at Age 10

  • L. PaganiC. Fitzpatrick
  • Psychology
    Health education & behavior : the official publication of the Society for Public Health Education
  • 2016
Compared with their never exposed peers, children exposed to transient and continuous early childhood household smoke showed proportionately less classroom engagement, which reflects task-orientation, following directions, and working well autonomously and with others.

A prenatal nicotine exposure mouse model of methylphenidate responsive ADHD-associated cognitive phenotypes

Frontal Cortex Proteome Perturbation after Juvenile Rat Secondhand Smoke Exposure

The effect of juvenile secondhand smoke exposure on the prefrontal cortex, a principal part of the brain involved in behavioral control, is characterized and the neuroproteomic response reflects a prominent perturbation within the glutamatergic synaptic system, suggesting aberrant, disorganized excitation as observed underlying psychiatric disorders.

Association between postnatal second-hand smoke exposure and ADHD in children: a systematic review and meta-analysis

The meta-analysis results suggested that postnatal exposure to SHS exposure may be a risk factor for ADHD and that SHS Exposure may be associated with some adverse behavioral outcomes.



Prenatal tobacco smoke and postnatal secondhand smoke exposure and child neurodevelopment

Prenatal tobacco and postnatal secondhand smoke exposure is consistently associated with problems in multiple domains of children's neurodevelopment and behavior, including irritability, oppositional defiant behavior, conduct disorders and attention deficit hyperactivity disorder.

Prenatal and Adolescent Exposure to Tobacco Smoke Modulates the Development of White Matter Microstructure

White matter microstructure in 67 adolescent smokers and nonsmokers with and without prenatal exposure to maternal smoking was examined, finding nicotine-induced disruption of the development of auditory corticofugal fibers may interfere with the ability of these fibers to modulate ascending auditory signals, leading to greater noise and reduced efficiency of neurocircuitry that supports auditory processing.

Developmental consequences of prenatal tobacco exposure

Results from published, in press, and conference proceedings from 2007 and 2008 that link in-utero tobacco exposure to neurodevelopmental outcomes in exposed offspring that appear to be moderated by genetic variability, neurobehavioral disinhibition, and sex are reviewed.

The Effects of Tobacco Smoke and Nicotine on Cognition and the Brain

The reviewed evidence suggests caution with the use of medicinal nicotine in pregnant mothers and older adults at risk for certain neurological disease, and the assessment of cognition-related genotypes to better understand the role of interactions between smoking/nicotine and variation in genotype in determining susceptibility to the neurotoxic effects of smoking and the putative beneficial effects of medicinal Nicotine.

Prenatal and postnatal environmental tobacco smoke exposure and children's health.

A large literature links both prenatal maternal smoking and children's ETS exposure to decreased lung growth and increased rates of respiratory tract infections, otitis media, and childhood asthma, with the severity of these problems increasing with increased exposure.

Secondhand Smoke Exposure and Neurobehavioral Disorders Among Children in the United States

The findings of the study underscore the health burden of childhood neurobehavioral disorders that may be attributable to secondhand tobacco smoke exposure in homes in the United States.

Maternal smoking and behavior problems of children.

Data from the population-based National Longitudinal Survey of Youth were used to investigate the possible association of maternal smoking and behavior problems among 2256 children aged 4 through 11 years.

Effects of maternal smoking in pregnancy on prenatal brain development. The Generation R Study

It is concluded that continuing to smoke during pregnancy leads to reduced growth of the foetal head, and further research should focus on the causal pathway from prenatal cigarette exposure via brain development to behavioural and cognitive functions.