Environmental perturbations lift the degeneracy of the genetic code to regulate protein levels in bacteria

@inproceedings{Subramaniam2012EnvironmentalPL,
  title={Environmental perturbations lift the degeneracy of the genetic code to regulate protein levels in bacteria},
  author={Arvind R. Subramaniam and Tao Pan and Philippe Cluzel},
  year={2012}
}
The genetic code underlying protein synthesis is a canonical example of a degenerate biological system. Degeneracies in physical and biological systems can be lifted by external perturbations thus allowing degenerate systems to exhibit a wide range of behaviors. Here we show that the degeneracy of the genetic code is lifted by environmental perturbations to regulate protein levels in living cells. By measuring protein synthesis rates from a synthetic reporter library in Escherichia coli, we… CONTINUE READING
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