Environmental modulation of both locomotor response and locomotor sensitization to the dopamine agonist quinpirole.

@article{Einat1993EnvironmentalMO,
  title={Environmental modulation of both locomotor response and locomotor sensitization to the dopamine agonist quinpirole.},
  author={Haim Einat and Henry Szechtman},
  journal={Behavioural pharmacology},
  year={1993},
  volume={4 4},
  pages={
          399-403
        }
}
The study tested whether differences in locomotor activation during chronic treatment result in differential behavioral sensitization induced by the D2/D3 dopamine agonist quinpirole. One group of rats received repeated injections of quinpirole in their home cage and another group received this treatment in an alternate environment of similar size. In the home cage, quinpirole induced less locomotion than in the non-home environment. When tested in activity monitors at the end of chronic… CONTINUE READING

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