Environmental influences on systemic lupus erythematosus expression.

  title={Environmental influences on systemic lupus erythematosus expression.},
  author={Diane L. Kamen},
  journal={Rheumatic diseases clinics of North America},
  volume={40 3},
  pages={401-12, vii}
The etiology of systemic lupus erythematosus (SLE) is unknown, but multiple genetic, epigenetic, and environmental risk factors have been implicated. The inheritance of genes alone is not sufficient for developing SLE, suggesting the influence of environmental triggers on disease expression. Despite the tremendous amount of progress in elucidating potential environmental risk factors for SLE, much more needs to be done. An interdisciplinary approach to studies of the causes and, ultimately… CONTINUE READING