Environmental estrogens alter early development in Xenopus laevis.

  title={Environmental estrogens alter early development in Xenopus laevis.},
  author={Cassandra L Bevan and Donna M. Porter and Anita Prasad and Marthe J. Howard and Leslie P. Henderson},
  journal={Environmental Health Perspectives},
  pages={488 - 496}
A growing number of environmental toxicants found in pesticides, herbicides, and industrial solvents are believed to have deleterious effects on development by disrupting hormone-sensitive processes. We exposed Xenopus laevis embryos at early gastrula to the commonly encountered environmental estrogens nonylphenol, octylphenol, and methoxychlor, the antiandrogen, p,p-DDE, or the synthetic androgen, 17 alpha-methyltestosterone at concentrations ranging from 10 nM to 10 microM and examined them… CONTINUE READING