Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats.

@article{Segovia2006EnvironmentalEP,
  title={Environmental enrichment promotes neurogenesis and changes the extracellular concentrations of glutamate and GABA in the hippocampus of aged rats.},
  author={Gregorio Segovia and Almudena G Yag{\"u}e and Jose Manuel Garc{\'i}a-Verdugo and Francisco Mora},
  journal={Brain research bulletin},
  year={2006},
  volume={70 1},
  pages={8-14}
}
The aim of the present study was to investigate the effects of environmental enrichment on the neurogenesis and the extracellular concentrations of glutamate and GABA in the hippocampus of freely moving young and aged rats. Male Wistar rats of 2 (young) and 25 (old) months of age were housed during 8 weeks in an enriched environment; control rats were kept in individual plastic cages during that same period of time. Rats were injected intraperitoneally with bromodeoxyuridine (BrdU; 40 mg/kg; 7… CONTINUE READING

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