Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity.

@article{Cortese2018EnvironmentalEI,
  title={Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity.},
  author={Giuseppe P Cortese and Andrew Olin and Kenneth J. O'Riordan and Rikki Hullinger and Corinna Burger},
  journal={Neurobiology of aging},
  year={2018},
  volume={63},
  pages={1-11}
}
Previous studies from our laboratory have shown that environmental enrichment (EE) in young rats results in improved learning ability and enhanced metabotropic glutamate receptor-dependent long-term potentiation (mGluR-dependent LTP) resulting from sustained activation of p70S6 kinase. Here, we investigated whether 1-month EE is sufficient to improve… CONTINUE READING