Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats.

@article{Buchhold2007EnvironmentalEI,
  title={Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats.},
  author={Britta Buchhold and Laurențiu Mogoantă and Yalikun Suofu and Alexander Hamm and Lary C Walker and C H Kessler and Aurel Popa-Wagner},
  journal={Restorative neurology and neuroscience},
  year={2007},
  volume={25 5-6},
  pages={467-84}
}
PURPOSE Aging is associated with a temporally dysregulated cellular response to ischemia as well as poor functional recovery. While environmental enrichment has been shown to improve the behavioral outcome of stroke in young animals, the effect of an enriched environment on behavioral and neuropathological recovery in aged animals is not known. METHODS Focal cerebral ischemia was produced by electrocoagulation of the right middle cerebral artery in 3 month- and 20 month-old male Sprague… CONTINUE READING

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