Environmental enrichment alters nerve growth factor-induced gene A and glucocorticoid receptor messenger RNA expression after middle cerebral artery occlusion in rats.

@article{Dahlqvist1999EnvironmentalEA,
  title={Environmental enrichment alters nerve growth factor-induced gene A and glucocorticoid receptor messenger RNA expression after middle cerebral artery occlusion in rats.},
  author={Per Dahlqvist and L Zhao and I M Johansson and Bengt Mattsson and Barbro Birgitta Johansson and Jonathan R Seckl and Tommy Olsson},
  journal={Neuroscience},
  year={1999},
  volume={93 2},
  pages={527-35}
}
Housing rats in an enriched environment after focal brain ischemia improves functional outcome without changes in infarct volume, suggesting neuroplastic changes outside the lesion. In this study, permanent occlusion of the middle cerebral artery was followed by housing in an enriched or a standard environment. Nerve growth factor-induced gene A and glucocorticoid receptor messenger RNA expression were determined by in situ hybridization two to 30 days after middle cerebral artery occlusion… CONTINUE READING

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