Environmental enrichment, prefrontal cortex, stress, and aging of the brain

  title={Environmental enrichment, prefrontal cortex, stress, and aging of the brain},
  author={Gregorio Segovia and Alberto del Arco and Francisco Mora},
  journal={Journal of Neural Transmission},
As a result of living in an enriched environment, the brain of animals undergoes molecular and morphological changes leading to improvements in learning and memory. These improvements correlate well with increase in neurogenesis, synaptic density, or neurotrophic factors. We review here, in the context of the literature, the experiments performed in our own laboratory on the effects of environmental enrichment on the dynamics of dopamine and acetylcholine in the prefrontal cortex under a… CONTINUE READING
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Effects of an enriched environment on the release of dopamine in the prefrontal cortex produced by stress and on working memory during aging in the awake rat

  • G Segovia, A Del Arco, M De Blas, P Garrido, F Mora
  • Behav Brain Res
  • 2008
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