Environmental control of autoimmune inflammation in the central nervous system.

@article{Rothhammer2016EnvironmentalCO,
  title={Environmental control of autoimmune inflammation in the central nervous system.},
  author={Veit Rothhammer and Francisco J. Quintana},
  journal={Current opinion in immunology},
  year={2016},
  volume={43},
  pages={
          46-53
        }
}
Multiple sclerosis (MS) is a chronic autoimmune inflammatory demyelinating disorder of the central nervous system (CNS), which causes severe disability and requires extensive medical attention and treatment. While the infiltration of pathogenic immune cells into the CNS leads to the formation of inflammatory lesions in its initial relapsing-remitting stage, late stages of MS are characterized by progressive neuronal loss and demyelination even without continued interaction with the peripheral… CONTINUE READING
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