Environmental conditions modulate degeneration and new dendrite growth in cerebellum of senescent rats

@article{Greenough1986EnvironmentalCM,
  title={Environmental conditions modulate degeneration and new dendrite growth in cerebellum of senescent rats},
  author={William T. Greenough and J. W. McDonald and Robert M. Parnisari and James E. Camel},
  journal={Brain Research},
  year={1986},
  volume={380},
  pages={136-143}
}
Spiny branchlets of cerebellar Purkinje neurons, thought to be sites of synaptic efficacy change during motor learning, degenerate during aging. To examine effects of behavioral experience on degeneration, Purkinje neurons were studied in aging rats housed for 4.5 months either under complex environment conditions promoting sensory-motor activity or in pairs in standard cages. Their data were compared with those of a baseline group of rats from standard cages sacrificed at the age of onset of… CONTINUE READING

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