Environmental chemical tributyltin augments adipocyte differentiation.

  title={Environmental chemical tributyltin augments adipocyte differentiation.},
  author={Hidekuni Inadera and Akiko Shimomura},
  journal={Toxicology letters},
  volume={159 3},
Scientific attention has been drawn to environmental factors that affect obesity and type II diabetes. Previously, acute organotin toxicosis was reported to induce hyperglycemia without morphological abnormalities in islet tissue, suggesting that these compounds have a direct effect on adipose tissue. Therefore, we investigated the effect of tributyltin (TBT) on adipocyte differentiation. When confluent 3T3-L1 cells were incubated with TBT for 2 days in the presence or absence of isobutyl… CONTINUE READING


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