Environmental challenge studies in laboratory animal allergy. Effect of different airborne allergen concentrations.

@article{Eggleston1995EnvironmentalCS,
  title={Environmental challenge studies in laboratory animal allergy. Effect of different airborne allergen concentrations.},
  author={Peyton A. Eggleston and Aftab A Ansari and Newton Franklin Adkinson and Robert B. Wood},
  journal={American journal of respiratory and critical care medicine},
  year={1995},
  volume={151 3 Pt 1},
  pages={640-6}
}
In order to examine the dose-dependence of the airway response to animal allergens we performed environmental challenges on 17 workers with documented IgE-mediated allergic reactions to laboratory rats. The 1-h environmental challenges were conducted in a vivarium during cage cleaning (high-allergen challenge), quiet sitting (low-allergen challenge), or in a remote location (sham challenge). During the high antigen conditions, mean Rat n 1 concentration was 166 +/- 28 ng/m3 compared with 9.6… CONTINUE READING
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