Envelope cross-reactivity between human immunodeficiency virus types 1 and 2 detected by different serological methods: correlation between cross-neutralization and reactivity against the main neutralizing site.

@article{Bttiger1990EnvelopeCB,
  title={Envelope cross-reactivity between human immunodeficiency virus types 1 and 2 detected by different serological methods: correlation between cross-neutralization and reactivity against the main neutralizing site.},
  author={Blenda B{\"o}ttiger and Anders Karlsson and P A Andreasson and Anders Naucl{\'e}r and Carlos Maur{\'i}cio de Castro Costa and E. C. J. Norrby and Gunnel Biberfeld},
  journal={Journal of virology},
  year={1990},
  volume={64 7},
  pages={3492-9}
}
A total of 70 human immunodeficiency virus type 1 (HIV-1) and 42 HIV-2 antibody-positive serum samples, collected from groups of individuals in which only one type of HIV prevails, were tested for cross-reactivity against HIV-2 and HIV-1 proteins by Western blot (WB) (immunoblot), radioimmunoprecipitation assay (RIPA), neutralization analysis, and enzyme-linked immunosorbent assay with as antigen synthetic peptides representing selected parts of the envelope (env) glycoproteins. Cross-reactions… CONTINUE READING

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