Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies.

Abstract

The number of antigen-specific naive CD8(+) T cells is believed to be important in the shaping of adaptive immune responses, and is predictive for the magnitude of priming responses in mouse models. Because of extremely low precursor frequencies, knowledge about these cells comes from indirect techniques and estimations. Here, we present a strategy based on… (More)
DOI: 10.1182/blood-2009-10-251124

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@article{Alanio2010EnumerationOH, title={Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies.}, author={C{\'e}cile Alanio and Fabrice Lema{\^i}tre and Helen K. W. Law and M. Zahid Hasan and Matthew L. Albert}, journal={Blood}, year={2010}, volume={115 18}, pages={3718-25} }