Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes.

@article{Stuart2006EntryOF,
  title={Entry of feline calicivirus is dependent on clathrin-mediated endocytosis and acidification in endosomes.},
  author={Amanda D. Stuart and T. D. Brown},
  journal={Journal of virology},
  year={2006},
  volume={80 15},
  pages={
          7500-9
        }
}
Feline calicivirus is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of Caliciviridae. We have examined the entry process of feline calicivirus (FCV). An earlier study demonstrated that acidification in endosomes may be required. We have confirmed this observation and expanded upon it, demonstrating, using drugs to inhibit the various endocytic pathways and dominant-negative mutants, that FCV infects cells via clathrin-mediated endocytosis… CONTINUE READING
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