Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner.

@article{Wang2014EntryOA,
  title={Entry of a novel marine DNA virus, Singapore grouper iridovirus, into host cells occurs via clathrin-mediated endocytosis and macropinocytosis in a pH-dependent manner.},
  author={Shaowen Wang and Xiaohong Huang and Youhua Huang and Xian Hao and Haijiao Xu and Mingjun Cai and Hai Wang and Q Qin},
  journal={Journal of virology},
  year={2014},
  volume={88 22},
  pages={13047-63}
}
UNLABELLED Iridoviruses are nucleocytoplasmic DNA viruses which cause great economic losses in the aquaculture industry but also show significant threat to global biodiversity. However, a lack of host cells has resulted in poor progress in clarifying iridovirus behavior. We investigated the crucial events during virus entry using a combination of single-virus tracking and biochemical assays, based on the established virus-cell infection model for Singapore grouper iridovirus (SGIV). SGIV… CONTINUE READING

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