Entropically Driven Helix Formation

@article{Snir2005EntropicallyDH,
  title={Entropically Driven Helix Formation},
  author={Yehuda Snir and Randall D. Kamien},
  journal={Science},
  year={2005},
  volume={307},
  pages={1067 - 1067}
}
The helix is a ubiquitous motif for biopolymers. We propose a heuristic, entropically based model that predicts helix formation in a system of hard spheres and semiflexible tubes. We find that the entropy of the spheres is maximized when short stretches of the tube form a helix with a geometry close to that found in natural helices. Our model could be directly tested with wormlike micelles as the tubes, and the effect could be used to self-assemble supramolecular helices. 
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