Entresto, a New Panacea for Heart Failure?

  title={Entresto, a New Panacea for Heart Failure?},
  author={Peter Khalil and Ghazal Kabbach and Sarmad Said and Debabrata Mukherjee},
  journal={Cardiovascular \& hematological agents in medicinal chemistry},
  volume={16 1},
Heart Failure (HF) is one of the main healthcare burdens in the United States and in the world. Many drugs are approved and used in practice for management of this condition; including beta blockers, diuretics, aldosterone antagonists, Angiotensin Converting Enzyme Inhibitors (ACEI's), and Angiotensin Receptor Blockers (ARBs). Recently, the Food and Drug Administration (FDA) approved a drug with brand name Entresto (Sacubitril/Valsartan or LCZ696), an angiotensin receptor neprilysin inhibitor… 
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