Entrapment of intracytosolic bacteria by septin cage-like structures.

@article{Mostowy2010EntrapmentOI,
  title={Entrapment of intracytosolic bacteria by septin cage-like structures.},
  author={Serge Mostowy and Matteo Bonazzi and M{\'e}lanie Anne Hamon and To Nam Tham and Adeline Mallet and Micka{\"e}l Lelek and Edith Gouin and Caroline Demangel and Roland Brosch and Christophe Zimmer and Anna Sartori and Makoto Kinoshita and Marc Lecuit and Pascale Cossart},
  journal={Cell host & microbe},
  year={2010},
  volume={8 5},
  pages={
          433-44
        }
}
Actin-based motility is used by various pathogens for dissemination within and between cells. Yet host factors restricting this process have not been identified. Septins are GTP-binding proteins that assemble as filaments and are essential for cell division. However, their role during interphase has remained elusive. Here, we report that septin assemblies are recruited to different bacteria that polymerize actin. We observed that intracytosolic Shigella either become compartmentalized in septin… CONTINUE READING

Figures and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 109 CITATIONS, ESTIMATED 70% COVERAGE

Investigation of septins using infection by bacterial pathogens.

  • Methods in cell biology
  • 2016
VIEW 21 EXCERPTS
CITES BACKGROUND & METHODS

Mitochondria mediate septin cage assembly to promote autophagy of Shigella

  • EMBO reports
  • 2016
VIEW 19 EXCERPTS
CITES RESULTS, BACKGROUND & METHODS

Use of zebrafish to study Shigella infection

  • Disease models & mechanisms
  • 2018
VIEW 7 EXCERPTS
CITES BACKGROUND

Septins and Bacterial Infection

  • Front. Cell Dev. Biol.
  • 2016
VIEW 10 EXCERPTS
CITES BACKGROUND

Myosin IIA is essential for Shigella flexneri cell-to-cell spread.

  • Pathogens and disease
  • 2014
VIEW 9 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Autophagy and bacterial clearance: a not so clear picture

  • Cellular microbiology
  • 2013
VIEW 9 EXCERPTS
CITES BACKGROUND

FILTER CITATIONS BY YEAR

2011
2019

CITATION STATISTICS

  • 2 Highly Influenced Citations

  • Averaged 9 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

Septin 11 Restricts InlB-mediated Invasion by ListeriaS⃞

  • The Journal of biological chemistry
  • 2009
VIEW 8 EXCERPTS

Unveiling the roles of autophagy in innate and adaptive immunity

  • Nature Reviews Immunology
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL