Entrapment in anti myelin-associated glycoprotein neuropathy

  title={Entrapment in anti myelin-associated glycoprotein neuropathy},
  author={PhD Catharina G. Faber and PhD Nicolette C. Notermans and PhD John H. J. Wokke and PhD Hessel Franssen},
  journal={Journal of Neurology},
Anti-myelin associated glycoprotein (MAG) neuropathy is a chronic disorder in which IgM antibodies react with Schwann cell glycoproteins, including MAG and peripheral myelin protein 22 (PMP22). Nerve conduction studies show features of axon loss and predominantly distal slowing consistent with demyelination. Because a genetic loss of PMP22 function yields hereditary neuropathy with liability to pressure palsies (HNPP), loss of PMP22 function due to anti- MAG antibodies may result in increased… CONTINUE READING