Entrainment Dissociates Transcription and Translation of a Circadian Clock Gene in Neurospora

  title={Entrainment Dissociates Transcription and Translation of a Circadian Clock Gene in Neurospora},
  author={Ying Tan and Zdravko Dragovic and Till Roenneberg and Martha Merrow},
  journal={Current Biology},
Circadian systems coordinate the daily sequence of events in cells, tissues, and organisms. In constant conditions, the biological clock oscillates with its endogenous period, whereas it is synchronized to the 24 hr light:dark cycle in nature. Here, we investigate light entrainment of Neurospora crassa to photoperiods that mimic seasonal changes. Clock gene (frequency, or frq) RNA levels directly reflect the light environment in all photoperiods, whereas the FRQ protein follows neither RNA… CONTINUE READING

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