Entorhinal cortex pre-alpha cell clusters in schizophrenia: quantitative evidence of a developmental abnormality.

@article{Falkai2000EntorhinalCP,
  title={Entorhinal cortex pre-alpha cell clusters in schizophrenia: quantitative evidence of a developmental abnormality.},
  author={Peter Falkai and Thomas Schneider-Axmann and William Honer},
  journal={Biological psychiatry},
  year={2000},
  volume={47 11},
  pages={937-43}
}
BACKGROUND Previous studies using semiquantitative or qualitative techniques demonstrated abnormalities of positioning of clusters of neurons (pre-alpha cells) in the entorhinal cortex in schizophrenia, suggesting a developmental mechanism could contribute to the illness. Recent quantitative studies of laminar thickness and laminar cell counts have been less consistent, and several failed to replicate the finding. However, none of the quantitative studies focused on the position of the pre… CONTINUE READING

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