Entorhinal cortex lesions disrupt fear conditioning to background context but spare fear conditioning to a tone in the rat.

@article{Majchrzak2006EntorhinalCL,
  title={Entorhinal cortex lesions disrupt fear conditioning to background context but spare fear conditioning to a tone in the rat.},
  author={Monique Majchrzak and Barbara Ferry and Alain R. Marchand and Karin Herbeaux and Alexandre Seillier and Alexandra Barbelivien},
  journal={Hippocampus},
  year={2006},
  volume={16 2},
  pages={114-24}
}
Recent studies have shown that the integrity of the entorhinal cortex (EC) is not required for simple contextual conditioning. In background contextual conditioning, i.e., when a phasic cue is present during training, the involvement of the EC is still a matter of debate. Therefore, the present work further examines whether the EC is required for background contextual conditioning using a tone as the phasic cue. Rats sustaining either excitotoxic lesions of the EC or sham-lesions were trained… CONTINUE READING

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