Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells

@article{Ylipaasto2003EnterovirusII,
  title={Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells},
  author={Petri Ylipaasto and Karin Klingel and A Michael Lindberg and Timo Otonkoski and Reinhard Kandolf and Tapani Hovi and Dr. M. Roivainen},
  journal={Diabetologia},
  year={2003},
  volume={47},
  pages={225-239}
}
It is thought that enterovirus infections cause beta-cell damage and contribute to the development of Type 1 diabetes by replicating in the pancreatic islets. We sought evidence for this through autopsy studies and by investigating known enterovirus receptors in cultured human islets. Autopsy pancreases from 12 newborn infants who died of fulminant… CONTINUE READING