Enterotoxigenic Escherichia coli (K88) induce proinflammatory responses in porcine intestinal epithelial cells.

@article{Devriendt2010EnterotoxigenicEC,
  title={Enterotoxigenic Escherichia coli (K88) induce proinflammatory responses in porcine intestinal epithelial cells.},
  author={Bert Devriendt and Edith Stuyven and Frank Verdonck and Bruno Maria Goddeeris and Eric Cox},
  journal={Developmental and comparative immunology},
  year={2010},
  volume={34 11},
  pages={1175-82}
}
Infections with F4(+) enterotoxigenic Escherichia coli (ETEC) causes severe diarrhoea in piglets, resulting in morbidity and mortality. F4 fimbriae are the key virulence factors mediating the attachment of F4(+) ETEC to the intestinal epithelium. Intestinal epithelial cells (IEC) are recently being recognized as important regulators of the intestinal immune system through the secretion of cytokines, however, data on how F4(+) ETEC affect this cytokine secretion are scarce. By using ETEC strains… CONTINUE READING

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