Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements
@article{Frankel1998EnteropathogenicAE, title={Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements}, author={Gad Frankel and Alan D. Phillips and Ilan Rosenshine and Gordon Dougan and James B. Kaper and Stuart Knutton}, journal={Molecular Microbiology}, year={1998}, volume={30} }
Enteropathogenic (EPEC) and enterohaemorrhagic Escherichia coli (EHEC) constitute a significant risk to human health worldwide. Both pathogens colonize the intestinal mucosa and, by subverting intestinal epithelial cell function, produce a characteristic histopathological feature known as the ‘attaching and effacing’ (A/E) lesion. Although EPEC was the first E. coli to be associated with human disease in the 1940s and 1950s, it was not until the late 1980s and early 1990s that the mechanisms…
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