Enteropathogenic Escherichia coli virulence genes encoding secreted signalling proteins are essential for modulation of Caco-2 cell electrolyte transport.

Abstract

The pathophysiology of enteropathogenic Escherichia coli (EPEC) diarrhea remains uncertain. In vitro, EPEC stimulates a rapid increase in short-circuit current (Isc) across Caco-2 cell monolayers coincident with intimate attaching and effacing (A/E) bacterial adhesion. This study has examined the roles of specific EPEC virulence proteins in this Isc… (More)

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@article{Collington1998EnteropathogenicEC, title={Enteropathogenic Escherichia coli virulence genes encoding secreted signalling proteins are essential for modulation of Caco-2 cell electrolyte transport.}, author={G K Collington and Ian Booth and Michael S. Donnenberg and James B. Kaper and Stuart Knutton}, journal={Infection and immunity}, year={1998}, volume={66 12}, pages={6049-53} }