Enterocytes adhere preferentially to collagen IV in a differentially regulated divalent cation-dependent manner.

@article{Moore1994EnterocytesAP,
  title={Enterocytes adhere preferentially to collagen IV in a differentially regulated divalent cation-dependent manner.},
  author={R G Moore and James L. Madara and R. John Macleod},
  journal={The American journal of physiology},
  year={1994},
  volume={266 6 Pt 1},
  pages={G1099-107}
}
Minor cell defects in epithelial sheets are a consequence of superficial injury in natural intestinal diseases. These defects are restored by migration of shouldering epithelial cells over the underlying matrix. Restitution of minor epithelial defects is facilitated by collagen IV (R. Moore, J. Madri, S. Carlson, and J. L. Madara. Gastroenterology 102: 119-130, 1992). Here we characterize enterocyte attachment to substrates and determine the role of divalent cations. Attachment and spreading of… CONTINUE READING