Enteric bacteria counteract lipopolysaccharide induction of antimicrobial peptide genes.

@article{Lindmark2001EntericBC,
  title={Enteric bacteria counteract lipopolysaccharide induction of antimicrobial peptide genes.},
  author={Hans Lindmark and Karin C. Johansson and Svenja St{\"o}ven and Dan Hultmark and Ylva Engstr{\"o}m and Kenneth S{\"o}derh{\"a}ll},
  journal={Journal of immunology},
  year={2001},
  volume={167 12},
  pages={6920-3}
}
The humoral immunity of Drosophila involves the production of antimicrobial peptides, which are induced by evolutionary conserved microbial molecules, like LPS. By using Drosophila mbn-2 cells, we found that live bacteria, including E. coli, Salmonella typhimurium, Erwinia carotovora, and Pseudomonas aeruginosa, prevented LPS from inducing antimicrobial peptide genes, while Micrococcus luteus and Streptococcus equi did not. The inhibitory effect was seen at bacterial levels from 20 per mbn-2… CONTINUE READING

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