Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs.

@article{Reeds1996EnteralGI,
  title={Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs.},
  author={Peter J. Reeds and Douglas Burrin and Farook Jahoor and Linda J. Wykes and Joseph F Henry and Eileen Frazer},
  journal={The American journal of physiology},
  year={1996},
  volume={270 3 Pt 1},
  pages={E413-8}
}
We studied the absorption of enteral glutamate and phenylalanine using isotopic tracer and arteriovenous difference techniques. Six piglets, implanted with portal, carotid, and gastric catheters and an ultrasonic portal flow probe received a 6-h intragastric infusion of [U-13C] glutamate and [2H] phenylalanine, with a high-protein diet offered one time each hour. Amino acid concentrations and the isotopic enrichments of all mass isotopomers of glutamate, glutamine, and phenylalanine were… CONTINUE READING
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