Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.

Abstract

Total parenteral nutrition (TPN) is essential for patients with impaired gut function but leads to parenteral nutrition-associated liver disease (PNALD). TPN disrupts the normal enterohepatic circulation of bile acids, and we hypothesized that it would decrease intestinal expression of the newly described metabolic hormone fibroblast growth factor-19 (FGF19… (More)
DOI: 10.1152/ajpgi.00280.2011

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@article{Jain2012EnteralBA, title={Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.}, author={Ajay K. Jain and Barbara J. Stoll and Douglas Guy Burrin and Jens Juul Holst and David D. Moore}, journal={American journal of physiology. Gastrointestinal and liver physiology}, year={2012}, volume={302 2}, pages={G218-24} }