Enteral IGF-I enhances fetal growth and gastrointestinal development in oesophageal ligated fetal sheep.

@article{Kimble1999EnteralIE,
  title={Enteral IGF-I enhances fetal growth and gastrointestinal development in oesophageal ligated fetal sheep.},
  author={Roy M. Kimble and Bernhard H. Breier and Peter Gluckman and Jane E Harding},
  journal={The Journal of endocrinology},
  year={1999},
  volume={162 2},
  pages={227-35}
}
Infants with upper gut atresia often have impaired intrauterine growth and gut function. IGF-I is important in fetal growth and is contained in amniotic fluid. We therefore wanted to test the hypothesis that IGF-I infused into fetal gut would reverse the effects of an upper gut obstruction on gut structure and growth in fetal sheep. At 90 days gestation… CONTINUE READING