Entamoeba histolytica collagen binding proteins.

  title={Entamoeba histolytica collagen binding proteins.},
  author={Jos{\'e} Luis Rosales-Encina and M S Campos-Salazar and M Rojkind Matluk},
  journal={Archives of medical research},
  volume={23 2},
Three main collagen binding proteins from trophozoites of E. histolytica have been isolated: 105 kDa, 56 kDa and 30 kDa. They display a type I collagenolytic activity. The enzyme behaves as a mammalian collagenase regarding to its activity, collagen degradation products and inhibitors. Antibodies against affinity-purified molecules inhibit the binding of trophozoites to collagen substrates. Indirect evidence suggests that the 30 kDa molecule is the putative collagen receptor. These surface… CONTINUE READING