Entactin promotes adhesion and long-term maintenance of cultured regenerated skeletal myotubes.

@article{Funanage1992EntactinPA,
  title={Entactin promotes adhesion and long-term maintenance of cultured regenerated skeletal myotubes.},
  author={Vicky L. Funanage and Susan M E Smith and M A Minnich},
  journal={Journal of cellular physiology},
  year={1992},
  volume={150 2},
  pages={251-7}
}
The basal lamina protein, laminin, has been shown to promote migration and proliferation of cultured skeletal myoblasts, resulting in increased myotube formation. However, skeletal myotubes adhere poorly to a laminin substrate, and long-term cultures of skeletal myotubes on laminin have not been achieved. We have found that cultured satellite cells from bupivacaine-damaged rat skeletal muscle actively proliferate and differentiate on a diluted Matrigel substrate composed of laminin, type IV… CONTINUE READING

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