• Corpus ID: 46492302

Entacapone/levodopa/carbidopa combination tablet: Stalevo.

  title={Entacapone/levodopa/carbidopa combination tablet: Stalevo.},
  journal={Drugs in R\&D},
  volume={4 5},
  • Published 2003
  • Medicine
  • Drugs in R&D
Entacapone (Comtess/Comtan) is Orion Pharma's original proprietary catechol-O-methyl transferase (COMT) inhibitor. Entacapone is able to slow down degradation of levodopa and improve the availability and efficacy of each levodopa dose, hence its use as a complement to levodopa/carbidopa in patients with Parkinson's disease. In order to simplify the daily dosing of these medications, Orion has developed an entacapone/levodopa/carbidopa combination tablet. Three tablet strengths are being…