Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine

@inproceedings{Smith2012EnsembleMO,
  title={Ensemble Modeling of the Likely Public Health Impact of a Pre-Erythrocytic Malaria Vaccine},
  author={Thomas A. Smith and Amanda Ross and Nicolas Maire and Nakul Chitnis and Alain Studer and Diggory Hardy and Alan Brooks and Melissa A. Penny and Marcel Tanner},
  booktitle={PLoS medicine},
  year={2012}
}
BACKGROUND The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (EPI) in areas of stable endemic transmission of Plasmodium falciparum, and have been calibrated for such settings. Their applicability to low transmission settings is unclear. Evaluations of the efficiency of different deployment strategies in diverse settings should consider uncertainties in model… CONTINUE READING