Enrofloxacin: pharmacokinetics and metabolism in domestic animal species.

  title={Enrofloxacin: pharmacokinetics and metabolism in domestic animal species.},
  author={Cristina L{\'o}pez-Cadenas and Matilde Sierra-Vega and Juan J Garc{\'i}a-Vieitez and M Jos{\'e} Diez-Li{\'e}bana and Ana M Sahag{\'u}n-Prieto and N{\'e}lida Fern{\'a}ndez-Mart{\'i}nez},
  journal={Current drug metabolism},
  volume={14 10},
Enrofloxacin is a fluorquinolone exclusively developed for use in veterinary medicine (1980). The kinetics of enrofloxacin are characterized, in general terms, by high bioavailability in most species and rapid absorption after IM, SC or oral administration. However, several studies reported that enrofloxacin showed low bioavailability after oral administration in ruminants. This drug has a broad distribution in the organism, excellent tissue penetration and long serum half-life. Also… CONTINUE READING

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