Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines.

Abstract

BACKGROUND Prostate cancer stem cells (PCSC) offer theoretical explanations to many clinical and biological behaviors of the disease in human. In contrast to approaches of using side populations and cell-surface markers to isolate and characterize the putative PCSC, we hypothesize that androgen deprivation leads to functional enrichment of putative PCSC… (More)
DOI: 10.1002/pros.22685

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@article{Seiler2013EnrichmentOP, title={Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines.}, author={Daniel Leonard Seiler and Junying Zheng and Gentao Liu and Shunyou Wang and Joyce M. Yamashiro and Robert Evan Reiter and J. Huang and Gang Zeng}, journal={The Prostate}, year={2013}, volume={73 13}, pages={1378-90} }