Enrichment of generated murine osteoclasts

  title={Enrichment of generated murine osteoclasts},
  author={Atsushi Shioi and Frederick Ross and Steven L Teitelbaum},
  journal={Calcified Tissue International},
Biochemical and molecular studies of osteoclasts generally require cells in a reasonable degree of purity. The chicken has been extremely useful in this regard, as abundant avian osteoclasts can be generated in vitro entirely from pure populations of marrow macrophage precursors. Propagation of murine osteoclasts is, in contrast, far less efficients, demanding the presence of stromal cells. The aims of this study were to develop a method by which murine osteoclasts generated in culture, can be… CONTINUE READING