Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial

@article{Klle2013EnrichmentOA,
  title={Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial},
  author={Stig-Frederik Trojahn K{\o}lle and Anne Fischer-Nielsen and Anders Bruun Mathiasen and Jens J{\o}rgen Elberg and Roberto Stefan Oliveri and Peter Viktor Glovinski and Jens Kastrup and Maria Kirchhoff and Bo Sonnich Rasmussen and M. L. Talman and Carsten Thomsen and Ebbe Dickmeiss and Krzysztof Tadeusz Drzewiecki},
  journal={The Lancet},
  year={2013},
  volume={382},
  pages={1113-1120}
}
BACKGROUND Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been reported. Therefore, methods to increase graft viability are needed. Here, we report the results of a triple-blind, placebo-controlled trial to compare the survival of fat grafts enriched with autologous adipose-derived stem cells (ASCs) versus non-enriched fat grafts. METHODS Healthy participants underwent two liposuctions taken 14 days apart: one for… CONTINUE READING
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